Police are investigating an affray in Laverton North on Saturday, April 29.
Investigators have been told a fight broke out between two large groups around 10pm.
The groups were gone on police arrival but a number of items, believed to be items used in the fight, were seized from the industrial complex on Boundary Road.
Police were able to ascertain a number of those involved had taken themselves to various hospitals across the western suburbs.
A 36-year-old Williams Landing man, 28-year-old Tarneit man and a 35-year-old Tarneit man are currently in hospital with serious injuries.
The investigation is ongoing and no arrests have been made at this stage.
Information to Crime Stoppers on 1800 333 000 or visit www.crimestoppersvic.com.au.